This article states that around 5% of non-depressed people go on to develop depression when they eat junk food of the baked-goods variety (like croissants, pecans spins and Twinkies) or fast food.
Link between fast food and depression confirmed
The authors assume the link is causal (fast/junk food causes depression), but I don't see why. Many people only eat fast food and carb-rich junk food when they're already depressed and want the temporary solace (and serotonin/insulin hit) of comfort food. It might be smarter to eat more trail mix, olives and avocados when we're depressed, and leave out the Twinkies, but the fact is they cost more.
So, is the fast food/junk food self-medication for depression, contributor to depression, or both? It makes more sense to view it as a sign that something is amiss, rather than leaping to the conclusion that fast/junk food itself is the problem.
When people need to self-medicate, they're going to find a way. And at least fast food is not going to cause as many accidents as alcohol, as much ruin as harder drugs, or as much disease as compulsive sex -- all of which are popular forms of self-medication for depression.
Something to consider... We need not leap right to the blaming mentality. We can treat these changes in habits as useful clues instead.
Bioscience is happening now that was science fiction 10 short years ago. Is it sensible? Is it cool? How does the weirdness of our systems change the game?
I don't care about what we believe, because that interferes with thinking. I care about what works.
addiction
aging
ANS
antidepressants
antioxidants
astrocytes
biomedicine
bioscaffolding
brain
cart/horse
circadian rythms
clinical advice
containment not cure
CRPS/RSD
culture
cure not containment
depression
Dept. of the Blitheringly Obv.
disease origins
drugs
electric stim
endocrine modulation
gender
genes
glia
HPA axis
immunity
immuno-modulation
implanted devices
inflammation
intestines
it's not imaginary
just a sip
knowing your info
legislation
memory/cognition
mitochondria
myelin
nanotech
neural cells
neuro
neuro tuning
neurotransmitters
no really?
nutrition
odd logic
perception
politics
POTS
reflections
side-effects
spinal cord
studies
tissue growth
tools/toys
vertigo
veterans
vision
what works
Saturday, March 31, 2012
Thursday, March 8, 2012
Repeated stress knocks out the prefrontal cortex
... In a number of ways.
This article describes a new finding which relates memory loss and cognitive dysfunction to a loss of glutamate receptors in the prefrontal cortex (PFC):
body=http%3A%2F%2Fwww.sciencedaily.com%2Freleases%2F2012%2F03%2F120307132202.htm&subject=How+repeated+stress+impairs+memory
They state that this is why the PFC tends to falter in the face of repeated stress: the receptors for one of the key neurotransmitters become depopulated, leaving fewer sites to accept the glutamate and allow that part of the brain to do its job.
Cognitive impairment in the face of repeated or chronic stress is not a monolithic problem, though. Memory and decision-making are probably the most complex of brain tasks, and there are plenty of things that go wrong when memory and cognition fail.
Other factors include dopamine depletion, leaving less of that transmitter to carry messages back from the PFC, thereby making executive decisions harder to make and still harder to follow through on. (I wrote a previous post on dopamine and decision making. I'll dig it up and link over.)
And then there's the adrenaline overproduction and overuse that characterizes chronic and repeated stress, leading to disruption of the hypothalamic-pituitary-adrenal axis (the body's entire signaling structure for body processes) which contributes to brain dysfunction in still more ways: by disrupting sleep, which disrupts memory formation and impedes logic; and by contributing to the rise of metabolic syndrome, creating less stable blood sugar -- which, in the brain, adds considerable insult to injury: a hungry brain is a low-functioning brain.
Take your vacations. Simplify your life. Move your body around regularly. Meditate early and often. If you cherish your brain, you might as well let it work -- and that means getting a half-Nelson on stress before it gets one on you.
Links:
The article on overuse of dopamine (on my Living Anyway blog): http://livinganyway.blogspot.com/2011/03/dopamine-poverty-and-pain-lighter-side.html
Another Biowizardry entry on neurotransmitters: http://biowizardry.blogspot.com/2011/08/scared-of-wrong-things-role-of-mao-in.html
This article describes a new finding which relates memory loss and cognitive dysfunction to a loss of glutamate receptors in the prefrontal cortex (PFC):
body=http%3A%2F%2Fwww.sciencedaily.com%2Freleases%2F2012%2F03%2F120307132202.htm&subject=How+repeated+stress+impairs+memory
They state that this is why the PFC tends to falter in the face of repeated stress: the receptors for one of the key neurotransmitters become depopulated, leaving fewer sites to accept the glutamate and allow that part of the brain to do its job.
Cognitive impairment in the face of repeated or chronic stress is not a monolithic problem, though. Memory and decision-making are probably the most complex of brain tasks, and there are plenty of things that go wrong when memory and cognition fail.
Other factors include dopamine depletion, leaving less of that transmitter to carry messages back from the PFC, thereby making executive decisions harder to make and still harder to follow through on. (I wrote a previous post on dopamine and decision making. I'll dig it up and link over.)
And then there's the adrenaline overproduction and overuse that characterizes chronic and repeated stress, leading to disruption of the hypothalamic-pituitary-adrenal axis (the body's entire signaling structure for body processes) which contributes to brain dysfunction in still more ways: by disrupting sleep, which disrupts memory formation and impedes logic; and by contributing to the rise of metabolic syndrome, creating less stable blood sugar -- which, in the brain, adds considerable insult to injury: a hungry brain is a low-functioning brain.
Take your vacations. Simplify your life. Move your body around regularly. Meditate early and often. If you cherish your brain, you might as well let it work -- and that means getting a half-Nelson on stress before it gets one on you.
Links:
The article on overuse of dopamine (on my Living Anyway blog): http://livinganyway.blogspot.com/2011/03/dopamine-poverty-and-pain-lighter-side.html
Another Biowizardry entry on neurotransmitters: http://biowizardry.blogspot.com/2011/08/scared-of-wrong-things-role-of-mao-in.html
Saturday, February 11, 2012
Numeracy: The educational gift that keeps on giving?
This is about what we used to call numeric literacy:
http://www.sciencedaily.com/releases/2012/02/120210133346.htm#.TzdCY4vl1xg.mailto
I have problems with using the word "numeracy" to mean "numeric literacy", but I can adapt. To me, the word "numeracy" means "of or relating to numbers"; therefore, to be numerate means to be of or relating to numbers, and that doesn't make sense.
http://www.sciencedaily.com/releases/2012/02/120210133346.htm#.TzdCY4vl1xg.mailto
I have problems with using the word "numeracy" to mean "numeric literacy", but I can adapt. To me, the word "numeracy" means "of or relating to numbers"; therefore, to be numerate means to be of or relating to numbers, and that doesn't make sense.
This spasm of reflexive linguistic conservatism will pass and then we can get to the point...
Numeric literacy (however you name it) results in better decisions. Those who are numerically literate are better able to understand information that's represented by quantities and numbers, and not be confused by sloppy descriptions and poor representations. They have better outcomes in health care, work and other areas where decision-making really pays off.
Numeric literacy (however you name it) results in better decisions. Those who are numerically literate are better able to understand information that's represented by quantities and numbers, and not be confused by sloppy descriptions and poor representations. They have better outcomes in health care, work and other areas where decision-making really pays off.
The fun part is, that this article's writer makes the point that the spin doctors are gonna pounce on this, as if they haven't already:
Caveat emptor, from here on out!
Then, remember your fifth grade math and see how the numbers add up. (The kinds of statistics that get published in the news rarely require anything more, so don't let the math intimidate you.) That intellectual integrity can save your life.
Saturday, January 14, 2012
Blood sugar and mood
"ScienceDaily (2012-01-10) -- Patients simultaneously treated for both Type 2 diabetes and depression improve medication compliance and significantly improve blood sugar and depression levels compared to patients receiving usual care, according to a new study."
http://www.sciencedaily.com/releases/2012/01/120110093559.htm?utm_source=feedburner&utm_medium=email&utm_campaign=Feed%3A+sciencedaily%2Fmind_brain+%28ScienceDaily%3A+Mind+%26+Brain+News%29
In plain English, this means that people with non-insulin-dependent diabetes need to be treated both for diabetes and depression; when that happens, twice as many get stable.
This falls under the Department of the Blitheringly Obvious, because -- as anyone who has hypoglycemia, or has dealt with diabetics knows -- depression is the first sign of low blood sugar; low or unstable blood sugar leads to poor decision-making, notably poor food choices; poor food choices lead to unstable blood sugar, and round and round we go.
To break the cycle, both must be addressed. Otherwise, the cycle continues feeding on itself... er, unfeeding on itself. Or something.
As anyone with common sense who has dealt with the mentally ill knows, the first intervention is a proper meal. It's simply amazing how things improve with a little real food inside.
Unstable blood sugar worsens pain, impairs memory, and limits cognitive function. Low blood sugar specifically creates an unhappy state.
A hungry brain is not a happy brain!
Treating type II diabetes without treating depression, or treating depression without treating underlying type II diabetes, is not a recipe for success. The fact that as many as one third of these diabetic patients even get better, is pretty remarkable. Treat both, and over 60% of these people go back to cheerful, stable, productive lives -- not needing sickleave, additional benefits, or other direct and indirect expenses.
Sounds like a good cost/benefit profile to me!
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